Effect of Chandraprabha Vati in Experimental Prostatic Hyperplasia and Inflammation in Rats
نویسندگان
چکیده
Chandraprabha vati, an Ayurvedic formulation, was studied for its effect in experimental prostatic hyperplasia induced by testosterone injection s.c for 21 days in rats and inflammation induced in rat hind paw by carrageenan injection s.c. The results showed that Chandraprabha vati at dosage of 100, 200 and 400 mg/kg orally for 21 days showed significant reduction of prostatic hyperplasia as indicated by decreased prostate weight and volume and hispathological observations. It also significantly inhibited carrageenan induced hind paw oedema in dose dependant manner. These results highlight the mechanism of its effect in prostate disorder like Benign Prostatic Hyperplasia (BPH) by inhibiting proliferative and inflammatory processes in prostate.
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